All info pulled from Lodestone. Official Patch Notes for 2.2 found here. This post only really includes where to start whole questlines and specific content info. It will be updated as more info becomes available.
Also very excited they are adding a button in the Party Members tab that will now auto sort your party list : Tanks > Healers > DPS
This can also be achieved with the text command /partysort or /psort
Vanity Unlock: Glamours
Pre-Requirements: Level 50
Entry Quest: A Self-improving Man
Quest NPC: Wiscard
Location: Mor Dhona X:22 Y:6
Vanity Item Purchase: Clear Prisms & Glamour Dispellers
Purchase NPC: / Location:
*Bango Zango / Limsa Lominsa Lower Decks – X:9 Y:11
* Maisentra / New Gridania – X: 11 Y:11
* Roarich / Ul’dah: Steps of Nald The Goblet – X:10 Y:9
Token Trade: Philosophy trade-in
NPC: Auriana
Location: Mor Dhona – Revenant’s Toll
Crafting: New Crafting Tools
Pre-Requirements: Level 50
Entry Quest: Just Tooling Around
Quest NPC: Guiding Star
Location: Revenant’s Toll X: 21 Y: 6
Crafting: Master Recipe Books Unlock
Pre-Requirements: Level 50 Disciple of the hand
Entry Quest: Submission Impossible
Quest NPC: Wiscard
Location: Mor Dhona X:22 Y:6
Crafting: Master Recipe Books for Glamours
Pre-Requirements: Level 50 crafter & have first completed: “Submission Impossible”
Quest NPC: Tataroga
Location: Revenant’s Toll X:22 Y:6
Crafting: Master Recipe Books for Crafting
Pre-Requirements: Level 50 crafter & have first completed: “Just Tooling Around”
Quest NPC: Talan
Location: Revenant’s Toll X:22 Y:6
Minion: Wind-Up Sun
Pre-Requirements: Access to the Isles of Umbra & have an Elixer in your inventory to trade
Quest NPC: Magic Pot
Location: Western La Noscea X:12 Y:36
Retainer Unlock: Ventures
Pre-Requirements: Level 17
Entry Quest: An Ill-conceived Venture
Quest NPC “troubled adventurer”
Location:
* Limsa Lominsa Lower Decks X:9 Y:11
* New Gridania X:11 Y:12
* Ul’dah – Steps of Nald X:9 Y:8
Log Unlock: Challenge Log
Pre-Requirements: Level 15 & must first complete “Call of the Sea”
Entry Quest: Rising to the Challenge
Quest NPC: I’tolwann
Location: Limsa Lominsa Upper Decks – X:11 Y: 10
Housing Unlock: Gardening
Pre-Requirements: Must have purchased estate land
Purchase NPC: Housing Merchant
Location:
* Mist – X:11 Y:11
* Lavendar Beds – X: 11 Y:8
* The Goblet – X:11 Y:8
Main Story Quest: Main Story Expansion start
Pre-Requirements: Level 50
Entry Quest: Still Waters
Quest NPC: Minfilia
Location: Mor Dhona – The Rising Stones (X:6 Y:5)
Relic Upgrade: Saga of the Zodiac
Pre-Requirements: Level 50 & must complete “A Relic Reborn” & equipped Zenith weapon
Entry Quest: Up in Arms
Quest NPC: Gerolt
Location: North Shroud X:30 Y:20
Quest NPC: Jalzahn
Location: North Shroud X:29 Y:19
North Shroud: Atma of the Archer
Western Thanalan: Atma of the Twins
Central Thanalan: Atma of the Scales
Middle La Nocea: Atma of the Ram
Outer La Nocea: Atma of the Lion
Lower La Nocea: Atma of the Fish
Western La Nocea: Atma of the Crab
Quest NPC:
Location: Mor Dhona X: Y:
Side Story Quest: Hildebrand
Pre-Requirements: Level 50 & have completed the 2.1 Hildebrand questline
Entry Quest: The Science of Deduction
Quest NPC: Ellie
Location: Eastern Thanlan X:10 Y: 16
NOTE: You need to go through the Hildebrand quests in order to get to “Battle on the Big Bridge” fight w/ Gilgamesh
Beast Tribe Questlines: Kobolds: 789th Order Dig
Pre-Requirements: Level 41 and must first complete main scenario quest ” In Pursuit of the Past”
Entry Quest: Highway Robbery
Quest NPC: Trachraet
Location: Limsa Lominsa – Upper Decks (X:12, Y:12)
Beast Tribe Questlines: Sahagin: Novv’s Nursery
Pre-Requirements: Level 44 and must first complete main scenario quest ” In Pursuit of the Past”
Entry Quest: They Came from the Deep
Quest NPC: R’ashaht Rhiki
Location: Limsa Lominsa – Upper Decks (X:13, Y: 12)
Dungeon: The Lost City of Amdapor
Pre-Requirements: Level 50, item lvl 55, and must have complete “The Ultimate Weapon”
Entry Quest: One Night in Amdapor
Quest NPC: E-Sumi-Yan
Location: Old Gridania X:6 Y:10
Dungeon: Halatali (Hard)
Pre-Requirements: Level 50, item lvl 55, and must have complete “The Ultimate Weapon”
Entry Quest: This Times’s for Fun
Quest NPC: Hugubert
Location: Mor Dhona X:22 Y: 8
Dungeon: Brayflox Longstop (Hard)
Pre-Requirements: Level 50, item lvl 55, and must have complete “The Ultimate Weapon”
Entry Quest: Curds and Slay
Quest NPC: Bloezoeng
Location: Mor Dhona X:22 Y: 8
Trial: The Whorleater (Leviathin Hard)
Pre-Requirements: Level 50, ilvl 60 and must first complete main story quest “Into the Heart of the Whorl”
Entry Quest: Lord of the Whorl
Quest NPC: Eynzahr Slafyrsyn
Location: Lower La Noscea X:24 Y:33
NOTE: Upon patch 2.3 going live, completion of The Howling Eye (Extreme), The Navel (Extreme), and The Bowl of Embers (Extreme) will no longer be required to challenge The Whorleater (Extreme) or Thornmarch (Extreme).
Trial: The Whorleater (Leviathin Extreme)
Pre-Requirements: Level 50, ilvl 80 & must complete “Through the Maelstrom” & “Bowl of Embers (EX)”
Entry Quest: Whorl of a Time
Quest NPC: Urianger
Location: Western Thanlan – The waking Sands X:6 Y:4 (also reported as X: Y:6)
Trial: Thornmarch (Extreme)
Pre-Requirements: Level 50, ilvl 80 & must complete “On the Properties of Primals” & “Bowl of Embers (EX)”
Entry Quest: The King Lives
Quest NPC: Urianger
Location: Western Thanalan – The waking Sands X:6 Y:4 (also reported as X: Y:6)
Raid: Second Binding Coil of Bahamut (Turn 6 – Turn 9)
Pre-Requirements: Level 50 and must first complete Turn 5 & “Alisaie’s Pledge”
Entry Quest: Another Turn in the Coil
Quest NPC: Urianger
Location: Western Thanlan – The Waking Sands X:6, Y:6 (also reported as X: Y:6)
Related Quest: ????(Name TBA – )
Quest NPC: Alisaie
Location: Northern Thanalan – X:20 Y: 17
Katella's Corner 
can’t wait for 2.2!! thanks for getting this list started early. : )))
you can also type short versions of the dance emotes. its in the patch notes as well
/sdance
/hdance
/bdance
/mdance
That will be handy! ^^ Thanks for posting! 🙂
great post! I totally used your blog for 2.1 as well ;D
Yay! Glad to hear it’s been useful! ^^
omg using this right now thankyouuu
Thank you! Thank you! Great guide!
“Help Me, Lord of the Dance” gives you /baldance, not sure where to get other dances yet
Step Dance
Quest: “Good for What Ales You”
NPC: Dodozan
Location: Limsa Lominsa Lower Decks – X:7 Y:12
Harvest Dance
Quest: “Saw That One Coming”
NPC: Eral
Location: New Gridania (12,13)
Manderville Dance
Simply participate in the 2.2 Hildibrand side-story. Keep going until you reach “The Hammer” quest.
I spent twenty minutes looking around the Golden Bazaar in Eastern Thanalan and can’t find Ellie anywhere. XIVDB.com apparently think the new Hildebrand quest requires you to finish the main story first.
Is this a thing?
You need to finish the first Hildebrand quest
Awesome! Thanks for this!
Should be “Leviathan” and not “Leviathin”
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Oh. Level 50 requirement to start Hildibrand. Awesome. No manderville for me. ;u;
You forgot the “Battle on the Big Bridge” trial, which is unlocked through the Hildabrand side quest line.
I guess its true that some may not realize to look for the Hildebrand quest start info to get to it. Added a note to the Hildebrand quest start mentioning it. Thanks! 🙂
its not central la nocea, its middle.
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